教科研成果 | 主持课题: 1 82003805 转筋草活性成分Terminamine K靶向组蛋白变体H2A.Z伴侣蛋白CHZ1抑制三阴性乳腺癌转移的机制研究 202101-202312 国家自然科学基金青年基金 2 201901D211471 Terminamine K通过靶向HDAC6调控组蛋白变体H2A.Z抑制乳腺癌转移的机制研究 201909-202209 山西省科学技术厅,山西省应用基础研究计划项目 3 2019L0666 HDAC6抑制剂还原响应型纳米递药系统在乳腺癌中的作用,202001-202112 山西省教育厅,山西省高等学校科技创新项目 一作SCI论文: 1. Overcoming Therapeutic Failure in Osteosarcoma via Apatinib-Encapsulated Hydrophobic Poly (ester amide) Nanoparticles Xiangyu Li,† a Liying Wang,† b Li Wang,† c Jiaming Yu, c Guohao Lu, c Wei Zhao, c Congxiu Miao,* a Changye Zou* d and Jun Wu * a,b Biomaterials Science 2020 Oct 27; 8(21):5888-5899. Royal Society of Chemistry UK, JCR Q2, IF 6.843 2. Terminamines K–S, Antimetastatic Pregnane Alkaloids from the Whole Herb of Pachysandra terminalis Xiang-Yu Li, Yang Yu, Miao Jia, Mei-Na Jin, Nan Qin, Chuan Zhao* and Hong-Quan Duan* molecules 2016, 21, 1283; doi:10.3390/molecules21101283, Moleculars Diversity Preservation International (MDPI), JCR Q2, IF 4.411 3. Unraveling the Metastatic Niche in Breast Cancer Bone Metastasis through Single-Cell RNA Sequencing. Xiangyu Li 1,†,*, Ziyu Gao 1,†, Meiling Yang 2,3, Ciqiu Yang 4, Dongyang Yang 4, 3 Wenhui Cui 1, Dandan Wu 5 and Jie Zhou 5,* Clinical and Translational Oncology, accept. 授权专利: 吴钧,赵蔚,李翔宇;一种新型聚酯化合物与其为载体的纳米药物及该药物的应用,发明专利,专利号:ZL 2020 1 0474210.X,专利权人:长治医学院。 |